Professor Larry I. Lipshultz: genetic research in male infertility

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Professor Larry I. Lipshultz: genetic research in male infertility

Larry I. Lipshultz (Figure 1), M.D., is Professor of Urology and Chief of the Scott Department of Urology’s Division of Male Reproductive Medicine and Surgery. Dr. Lipshultz, who holds the Smith Chair in Reproductive Medicine, is a well-known authority on abnormalities of male reproduction, erectile dysfunction, and male hormone therapy. He received his medical training at the University of Pen...

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I-38: Search for Genetic Causes of Male Infertility

Background: We are convinced that better infertility treatment will only be achieved with a better under understanding of the molecular mechanisms specific to each patient. To that effect we want to indentify genes involved in male infertility. Materials and Methods: We screened cohorts of infertile men to identify the cause of their infertility. Results: Our team has identified and caracterize...

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I-6: Azoospermia Factor in Male Infertility

Background The human Y chromosome is essential for human sex determination and male germ cell development and maintenance. In 1996, Vogt et al. identified three recurrently deleted regions in Yq11 termed the azoospermia factor (AZF). The AZF region is subdivided into three non-overlapping sub-regions called AZFa, AZFb and AZFc and microdeletion in these regions is the most important etiology of...

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Genetic Testing in Male Infertility

Infertility is a major health problem which affects approximately 22% of married couples in reproductive age. The apparent increased incidence of male infertility, in parallel with the widespread use of in vitro fertilization (IVF), raises concern as to the impact of advanced assisted conception techniques in transmitting genetic anomalies to the offspring. Recent research has widely focused on...

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Genetic Causes of Male Infertility

Infertility is a major health problem today, affecting about 15.0% of couples trying to have a child. Impaired fertility of the male is causative in 20.0% of infertile couples and contributory in up to another 30.0-40.0%. Infertility already affects about 5.0-7.0% of the general male population and may further increase in the future, considering the apparent trend of declining sperm count in in...

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ژورنال

عنوان ژورنال: Translational Andrology and Urology

سال: 2016

ISSN: 2223-4683,2223-4691

DOI: 10.21037/tau.2016.06.14